Superoxide dismutase (SOD) is an important part of the antioxidant enzyme system in biological systems. It is an antioxidant metalloenzyme and is widely distributed in microorganisms, plants and animals. According to the different metal prosthetic groups, SOD can be divided into copper-zinc superoxide dismutase (Cu/Zn-SOD), manganese-containing superoxide dismutase (Mn-SOD) and iron-containing superoxide dismutase ( Fe-SOD) etc. Free radicals can cause damage to human tissues and cell structures. This damage is called oxidative stress. SOD can catalyze the disproportionation of superoxide anion free radicals to generate oxygen and hydrogen peroxide in vivo. Catalase (CAT) in vivo ) and peroxidase (POD) will immediately decompose hydrogen peroxide into completely harmless water. Therefore, SOD plays a crucial role in the balance of oxidation and anti-oxidation in the body, and is of great significance to the occurrence of diseases and the study of human anti-aging.

Functions

           SOD plays an important role in human health. Its functions mainly include improving sleep quality, enhancing memory, improving body immunity, anti-aging, enhancing wound healing ability, improving vision, preventing senile cataract, lowering blood pressure, blood lipid and cholesterol, and inhibiting cardiovascular and cerebrovascular diseases. , Enhance liver and gallbladder function, inhibit cancer cells to prevent tumors, prevent Alzheimer‘s disease, etc., can be used in food, health products, medicine and cosmetics fields, such as food additives, health products to improve immunity, anti-inflammatory drugs, anti-tumor drugs, senile Cataract drugs, cardiovascular and cerebrovascular disease drugs, etc., anti-aging, whitening, freckle skin care products. Around the age of 30, the SOD in the human body begins to decrease, both in quantity and vitality, and it is necessary to adjust the balance of free radicals in the body through exogenous supplementation. SOD can have the following positive effects on the human body:

       1. Scavenging free radicals, boosting immunity, meliorating sleep, enhancing memory, anti-aging.

           SOD can improve the body‘s resistance to external disease-inducing factors and adaptability to overloaded environments, and can quickly decompose free radicals and eliminate tissue and cell lipid peroxidation.

       2. Effectively relieve gout, or even cure it completely.

           Uric acid is the decomposition product of purine, and it is an antioxidant synthesized by the human body to resist free radicals. Therefore, the increase of uric acid means that there are too many free radicals in the body. A vicious cycle of death.   Although SOD is an antioxidant like uric acid, the difference is that SOD itself exists in the human body, so it is safe, and it uses free radicals as the only substrate. Therefore, SOD‘s influence and inhibition on free radicals are unmatched by          other antioxidants. . Theoretically, SOD has the possibility of completely reversing hyperuricemia. At present, experts have obtained better-than-expected results through animal experiments and human clinical trials.

       3. Effectively joint pain relief, potential enzymes for the treatment of osteoarthritis (OA).

           A large number of studies have shown that oxidative stress plays an important role in the development of osteoarthritis (OA) by participating in processes such as intracellular signaling, chondrocyte aging and apoptosis, extracellular matrix          synthesis and degradation, and synovial inflammation. important role. Therefore, improving the body‘s antioxidant capacity is considered to be a feasible solution for the treatment of OA. SOD is one of the important components of the body‘s        antioxidant enzyme system, which can quickly and efficiently scavenge reactive oxygen radicals (ROS), making it a potential enzyme drug for the treatment of ROS-related diseases.

       4. Effectively reducing blood lipid, blood pressure, cholesterol, blood viscosity, preventing Alzheimer’s disease.

           Human SOD content was negatively correlated with disease. The content of SOD in the human body is continuously reduced, and oxygen free radicals are continuously generated. After cross-linking with the proteins in the blood vessel wall, the   blood vessel wall is thickened and hardened, the official cavity is narrowed, the resistance in the blood vessel is increased, and the blood is thick, thereby causing various heart diseases. Vascular disease.

       5. Preventing senile cataract, improving eyesight.

           Excessive oxygen free radicals in the eye will cause protein changes in the eye, and at the same time, the plasma membrane of the lens will be peroxidized, forming insoluble products that accumulate in the middle of the lens, resulting in             cataracts.

       6. Ameliorating diabetes mellitus.

           Diabetes is a genetically prone endocrine and metabolic disease. Supplementing SOD in time can rejuvenate and accelerate the division of islet cells controlled by harmful free radicals. Insulin also becomes vigorous, which is important for           preventing diabetic complications and protecting the body to secrete insulin. Play an important role.

       7. Strengthening liver functions.

           Oxygen free radicals can cause damage to the liver cell membrane, leading to degeneration and necrosis of liver cells, and damage to liver tissue, thereby damaging the liver. SOD can alleviate the level of toxins in the blood, prevent hepatic        coma, mitigate blood ammonia, moderate the burden on the liver, and improve liver function.

       8. Treating prostatitis, regulating menstrual period, postponing menopause.

           SOD has strong antioxidant capacity, can inhibit the synthesis and release of prostaglandins and other inflammatory factors, improve inflammation, and restore the prostate to a healthy state. SOD can also protect the female endocrine system,     regulate the female menstrual cycle, irregular menstruation, restore the collagen system, and delay menopause.

       9. Enhancing joint motion, preventing arthritis.

           SOD can help the human body quickly recover physical strength, significantly increase grip strength, shorten the time of morning stiffness, alleviate joint pain and swelling, and moderate ESR, ameliorate joint shape, improve joint mobility, and      prevent osteoarthritis and rheumatoid arthritis.

       10. Preventing cancer, alleviating side-effects of cancer therapy.

           Free radicals cause DNA oxidation, damage or cross-linking changes, denaturation of nucleic acids, etc., and eventually lead to gene mutation. Supplementation of SOD can prevent the occurrence and development of tumors and alleviate the     side effects during radiotherapy and chemotherapy.

       11. Helping with wound healing.

           SOD has super antioxidant and anti-inflammatory functions, can quickly repair damaged cells and tissues, and achieve rapid wound healing. In addition, SOD also plays a prominent role in anti-radiation, anti-fatigue, improvement of initial             emphysema, and prevention and treatment of autoimmune diseases.

       12.  Skin-whiting, spots-removing, anti-wrinkles.

           Oxygen free radicals are the main culprit of pigmentation and can act on the human body to react to form pigmentation on the skin surface, such as deposition spots, age spots, freckles, melasma and pigmentation disorders. SOD effectively       removes free radicals, prevents pigmentation, removes existing pigment deposits in the skin, and increases skin moisture, so that the skin is not tight.

           SOD can be derived from animal blood, plants, it can be sourced from microbial fermentation too. Animal derived SOD is heterologous protein and unstable in room temperature, it is also potentially contaminated by viruses in the animal blood, it is prohibited to use in human body by EU and WHO. Plants derived SOD is only-a-few and hard-to-extract, so it’s costly. And microbial fermented SOD can solve all the problems, will attract more and more attentions from all around the globe.

Features

       Modern gene engineering and advanced fermentation techniques are used to produce Pallas top-quality SOD products, which are much cost-efficient. Pallas SOD products are more advantageous for below reasons:

       1. Sourced from fermentation process, non-viruses and other cross-contaminations;

       2. High activity, biological activity reaches >100,000U/g;

       3. Biological activity is more than 10,000 U/mg;

       4. Purity is more than 95% by electrophoresis method;

       5. Thermostable under 90℃ for 120 minutes;

       6. Stable under pH 3.0-11.0 and room temperature for 2 years;

       7. Well-absorbed with low molecular weight;

       8. Good bioavailability.