β-glucan


DESCRIPTION

Fermented β-Glucan is a kind of glucan with every 3 unit of β-1,3 backbone binding with one unit of β-1,6 branch, forming triplex structure, the culture is collected in sea. Based on such unique triplex structure, Fermented β-Glucan can bind with several cells locus like CR3, Dectin-1, activating human immune cells, including macrophage, neutrophil, natural killer. These immune cells will stimulate the immune system to secrete cytokines (IL-1, IL-6 etc.). With state of the art fermentation processes, Fermented β-Glucan retains active ingredients of the culture and good solubility, which is a unique and novel glucan in the world. In Cosmetics, Fermented β-Glucan shows outstanding properties and efficiency, strengthening skin immunity, anti-aging, antiallergic, repairing skin, moisturizing etc., which is one of the best quality active ingredients in current cosmetics market.

Comparison to other β-glucans

Parameters

Fermented β-Glucan

Yeast β-Glucan

Oats β-Glucan

Solubility in water

Soluble

Insoluble

Soluble

Producing Process

Fermentation

Extract

Extract

Source

Culture from sea

Yeast Cell

Cereal

Molecular Structure

β-1,6 branches

β-1,3 backbone

β-1,6 branches

β-1,3 backbone

Mix of β-1,3 and β-1,4

Percentage of β-1,3 linkage

65%

85%

10%

Percentage of β-1,6 linkage

35%

15%

0%

Percentage of β-1,4 linkage

0%

0%

90%

Thermostability

++++

+++

+++

pH Stability

+++++

++

+++

Moisturizing

+++++

++

+

Antiallergic

+++++

++

++


FUNCTIONS

² Increase immunity

² Anti-aging

² Anti-wrinkle and fine lines

² Repair skin

² Anti-allergic and anti-inflammation

² Moisturize and film

² Promote wound healing and skin regeneration

² Prevent and fade striae gravidarum


PROPERTIES
 

² Unique triplex structure, specifically binding with Dectin-1, CR3 etc., activating Langerhans’ cells, macrophage, neutrophil, NK, T-cells, strengthen skin immunity

² Accelerating the proliferation of Langerhans’ cells

² Scavenging free radicals

² Accelerating cytokines to create AP-1, NF-1, IL-1, IL-10 and TNF-β etc.

² Promoting the proliferation of fibroblast and synthesis of collagen and elastin

² Boosting the concentration of leukin, cytokinin and special antibodies (such as IgM)

² Degrading metalloprotease, which are enzymes hydrolyzing collagen and elastin

² Regaining balance of TH1/TH2, inhibiting the increasing of IgE

² Inhibiting degranulation of mast cells

² Promoting production of epidermal growth factor (EGF) and angiogenic factor (AF)

² Promoting production of natural moisturizing factor (NMF)

² Blocking allergens

² Skin permeability

² Large molecule produce a soft, breathable and moisturizing film on the skin


FEATURES
 

² Best water-solubility

² Best permeability

² Best skin-friendly

² Best stability

² Best cooperativity

² Non medical modification

² Safe and efficient

² DMF registration


DOSAGE & PACKAGE

Dosage: 1-20% (based on 1% β-glucan concentration)

Package: 20kg/bucket 


STORAGE CONDITION & SHELF LIFE

Storage: Stored in cool and dry place protected from light, keep drum close when not in use.
Shelf life: 24 months under prescribed storage conditions and airtight packing.